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Chapitre 11 : Biosensors for on-line monitoring of penicillin during its production by fermentation.

Abstract : An enzyme sensor has been developed for the on-line monitoring of penicillin V during its production by fermentation. The enzyme is crosslinked as a very fine film to the sensitive end of a pH transducer, using the spraying method. The biosensor is incorporated in a flow injection analysis (FIA) system within a home-made stirred flow detection cell. This new and improved biosensor shows good stability and large concentration measuring range. Penicillin-V in fermentation broth is detected during the whole HPLC method. On-line measurements are achieved through the automation of the FIA system.
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https://hal-emse.ccsd.cnrs.fr/emse-00494449
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Submitted on : Wednesday, June 23, 2010 - 11:30:06 AM
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  • HAL Id : emse-00494449, version 1

Citation

Canh Tran-Minh, Helmut Meier. Chapitre 11 : Biosensors for on-line monitoring of penicillin during its production by fermentation.. Rogers, K.M. ; Mulchandani, A. ; Zhou, W. Biosensor and Chemical Sensor Technology. Process Monitoring and Control, 11, American Chemical Society, pp.110-115, 1995, ACS Symposium Series 613. ⟨emse-00494449⟩

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