This paper analyses the performance of supply chains by using agent-based simulation. The proposed agents are based on the Supply Chain Operations Reference (SCOR) model. Most of the time, indicators and negotiation mechanisms within a supply chain are still primarily designed for local management (one-to-one relationship). The paper discusses different effects of supply chain configurations and the competitive environment on SCOR performance indicators from a global point of view. A modified version of a traditional SCOR indicator is introduced with the a priori knowledge of the network connectivity.