Acoustic emission of pharmaceutical products during powder compaction

Eric Serris 1, 2, 3, * Laurent Périer-Camby 1, 2, 3 Gérard Thomas 1, 2, 3 Marie Desfontaines 4 Gilbert Fantozzi 4
* Auteur correspondant
1 LPMG-EMSE - Laboratoire des Procédés en Milieux Granulaires
2 SPIN-ENSMSE - Centre Sciences des Processus Industriels et Naturels
3 ProcESS-ENSMSE - Département Procédés et évolution des systèmes avec solides
4 MATEIS - Matériaux, ingénierie et science [Villeurbanne]
Abstract : Acoustic emission measurements aim at understanding and distinguishing all the phenomena that occur during powder compaction of pharmaceutical products. Those phenomena are granular rearrangement, fragmentation and visco-plastic deformation of grains or granules. Other considerations such as specific area and porosity evolutions versus compaction pressure provide valuable data on domains where whether fragmentation or visco-plastic deformation could be predominant. Relationships between acoustic emissions and such phenomena occurring during comp action of pharmaceutical powders are proposed. For instance, compaction of brittle products like aspirin or saccharose produces strong acoustic emission whereas compaction of starch exhibiting a high visco-plastic behaviour produces a low acoustic emission.
Keywords : acoustic emission pharmaceutical powders compaction granular rearrangement fragmentation visco-plastic deformation specific area porosity
Type de document :
Communication dans un congrès
Yugi Kishino. Fourth International Conference on Micromechanics of Granular Media, May 2001, Sendaï, France. Balkema, pp.ISBN=90-2651-826-9, 2001
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https://hal-emse.ccsd.cnrs.fr/emse-00719202
Contributeur : Andrée-Aimée Toucas <>
Soumis le : jeudi 19 juillet 2012 - 14:42:14
Dernière modification le : jeudi 29 mars 2018 - 17:12:32
Document(s) archivé(s) le : samedi 20 octobre 2012 - 02:41:27

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  • HAL Id : emse-00719202, version 1

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Eric Serris, Laurent Périer-Camby, Gérard Thomas, Marie Desfontaines, Gilbert Fantozzi. Acoustic emission of pharmaceutical products during powder compaction. Yugi Kishino. Fourth International Conference on Micromechanics of Granular Media, May 2001, Sendaï, France. Balkema, pp.ISBN=90-2651-826-9, 2001. 〈emse-00719202〉

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