Rendering the supply chain more eco-friendly is an innovative idea progressively adopted by industry. Our research focuses on the CO2 equivalent emissions along the supply chain due to freight energy use and storage. A supply chain model based on discrete event simulation was developed. The model uses reorder point production management policy (ROP) within a make to stock (MTS) demand response strategy. Manufacturing capability is also taken into account using an overall equipment effectiveness indicator (OEE). In addition, the location of the firms and their types of products are modelled. The purpose is to compare supply chain CO2 equivalent emissions of different configurations. This method is applied to two industrial cases: Carrier (UTC group), a large cooler manufacturer and Zannier group, a textile industry. The principle objective of the study is to conduct pertinent experiments to give green guidelines to Carrier and Zannier group.