This paper aims to tackle issues related to the (re-)configuration of Smart Objects. These latter are composed specifically of smart sensors that embed basic sensors, a micro-controller and software snippets as well. In order to make this (re-)configuration feasible at runtime, we propose a semantic Web based approach that relies on a set of ontology modules together with a set of logical rules and reasoning processes to drive the (re-)configuration mechanism while taking into account, at the same time, requirements of the application domain. We validate our approach by means of a prototype that shows relevance of developed ontologies and (re-)configuration mechanism.