Virtual simulation can help students and enterpriseemployees to understand the company systematically and gain insights into the complexity and uncertaintyof the enterprise's digital innovation. The design focus of the virtualsimulation teaching platform needs to base on the business and data of the enterprise. Considering authenticity and interest, the simulation rules are designed to adapt tothe simulation needs of different business situations of various enterprises in a more flexible way. Therefore, this paper proposes a three-layer framework and implementation Methodology for extracting and configuring simulation rules, which can realize simulations of different business quickly and provide support for teachersin teaching. The implementation methodology of rule configuration serves for the three-layer framework. The paper takes rule configuration of a virtualsimulation as a caseto illustrate the proposed framework and methodology.